New Medical Device to Detect Precancerous Lesions in the Esophagus Wins 2020 Edison Award

A medical device based on technology developed by three faculty members from Case Western Reserve University and University Hospitals Cleveland Medical Center (UH) has won a prestigious 2020 Edison Best New Product Award. EsoCheck, a device designed to help detect precancerous changes in the esophagus, was named a “Silver” winner of the 2020 Edison BestContinue reading “New Medical Device to Detect Precancerous Lesions in the Esophagus Wins 2020 Edison Award”

Regular Exercise Helps Patients Combat Cancer

OUTRUNNING CANCER: Tumors on the lungs of sedentary mice (left) and animals that ran on wheels (right) after injection with melanoma cells. L. PEDERSEN ET AL., CELL METAB, 2016 Bente Klarlund Pedersen Mathilde was diagnosed with breast cancer at the age of 44. Doctors treated her with surgery, chemotherapy, and radiation, and Mathilde’s physician informedContinue reading “Regular Exercise Helps Patients Combat Cancer”

Using artificial intelligence to determine whether immunotherapy is working

Case Western Reserve researchers use AI with routine CT scans to predict how well lung cancer patients will respond to expensive treatment based off changes in texture patterns inside and outside the tumor. Scientists from the Case Western Reserve University digital imaging lab, already pioneering the use of artificial intelligence (AI) to predict whether chemotherapyContinue reading “Using artificial intelligence to determine whether immunotherapy is working”

Study on cannabis chemical as a treatment for pancreatic cancer may have ‘major impact,’ Harvard researcher says

Scientists from Harvard University’s Dana-Farber Cancer Institute have found evidence that a chemical derived from cannabis may be capable of extending the life expectancy for those with pancreatic cancer. Pancreatic cancer makes up just 3 percent of all cancers in America. But with a one-year survival rate of just 20 percent (and five-year survival rateContinue reading “Study on cannabis chemical as a treatment for pancreatic cancer may have ‘major impact,’ Harvard researcher says”

A new 3-D printed ‘sponge’ sops up excess chemo drugs

Bringing the filtering abilities of a fuel cell into the blood vessels of living organisms, a new device could cut down on toxic effects of cancer treatment. At the heart of this approach — recently tested in pigs — is a tiny, cylindrical “sponge” created by 3-D printing. Wedged inside a vein near a tumorContinue reading “A new 3-D printed ‘sponge’ sops up excess chemo drugs”

New research into why elephants are so highly protected from cancer

by Laura Elizabeth Mason Elephants have developed a way to resist cancer, by resurrecting a ‘zombie’ gene known as leukemia inhibitory factor 6 (LIF6). Activated LIF6 responds to damaged DNA and efficiently kills cells that are destined to become cancer cells. Cancer is a complex genetic disease that is caused by specific changes to theContinue reading “New research into why elephants are so highly protected from cancer”

Elephants Revived a “Zombie” Gene that May Fend Off Cancer

Elephants’ secret to their low rates of cancer might be explained in part by a so-called zombie gene—one that was revived during evolution from a defunct duplicate of another gene. In the face of DNA damage, elephant cells fire up the activity of the zombie gene LIF6 to kill cells, thereby destroying any cancer-causing geneticContinue reading “Elephants Revived a “Zombie” Gene that May Fend Off Cancer”

Reducing NOVA1 gene helps prevent tumor growth in most common type of lung cancer

Lung cancer seen on chest X ray. Researchers have identified a gene that when inhibited or reduced, in turn, reduced or prevented human non-small cell lung cancer tumors from growing. When mice were injected with non-small cell lung cancer cells that contained the gene NOVA1, three of four mice formed tumors. When the mice wereContinue reading “Reducing NOVA1 gene helps prevent tumor growth in most common type of lung cancer”

Researchers identify dozens of new gene changes that point to elevated risk of prostate cancer in men of European descent

As the result of a six-year long research process, Fredrick R. Schumacher, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent. The findings, publishedContinue reading “Researchers identify dozens of new gene changes that point to elevated risk of prostate cancer in men of European descent”

Rapamycin lotion reduces facial tumors caused by tuberous sclerosis

Researching tuberous sclerosis from the left are Adelaide Hebert, M.D.; John Slopis, M.D.; Mary Kay Koenig, M.D.; Joshua Samuels, M.D., M.P.H.; and Hope Northrup, M.D. PHOTO CREDIT Maricruz Kwon, UTHealth Addressing a critical issue for people with a genetic disorder called tuberous sclerosis complex (TSC), doctors at The University of Texas Health Science Center atContinue reading “Rapamycin lotion reduces facial tumors caused by tuberous sclerosis”