Half of all cases of Alzheimer’s disease may be misdiagnosed.

 

It’s currently impossible to definitively diagnosis Alzheimer’s disease while the patient is alive.  Researchers recently analyzed around 800 brains from Alzheimer’s patients after they died, and learned that only about half of them actually had the disease.  The other half suffered from other forms of dementia.  A reliable way to diagnose the specific type of dementia from which patients are suffering is critical to guiding treatment for patients and for researching the disease processes.

http://pagingdrgupta.blogs.cnn.com/2011/02/23/half-of-alzheimers-cases-misdiagnosed/?hpt=T2

Mental Illness and the Sun

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It’s been known for a long time that winter-born babies are more likely to develop severe mental illness, including schizophrenia, depression and seasonal affective disorder.  Researchers at Vanderbilt and the University of Alabama may have identified clues as to how seasonal sunlight exposure could affect expression of clock genes that control our normal biological rhythms.

https://www.scientificamerican.com/article.cfm?id=blame-it-on-winter

The Placebo Response

 Originally discovered by an Allied forces Army nurse in WWII, the placebo response continues to mystify physicians, researchers, and pharmaceutical companies alike.  Our body’s physiological response to medicine is largely impacted by our interpretation of social cues, anticipation of reward, and our beliefs and expectations.  This complex constellation of factors in the mind can yield significant clinical improvement in patients taking nothing more than inert sugar pills.  As Steve Silberman describes, “The placebo response doesn’t care if the catalyst for healing is a triumph of pharmacology, a compassionate therapist, or a syringe of salt water.  All it requires is a reasonable expectation of getting better.  That’s potent medicine.”  Interestingly, it also works the other way – the ‘Nocebo Response.’

http://www.wired.com/medtech/drugs/magazine/17-09/ff_placebo_effect?currentPage=all

Fake Bus Stop

 

Pioneered at the Benrath Senior Centre in Düsseldorf, some treatment centers are now encouraging Alzheimer’s sufferers to wait at a fake bus stop as  part of pioneering treatment for the disease.

http://www.radiolab.org/blogs/radiolab-blog/2010/mar/23/the-bus-stop/

http://www.fastcompany.com/1598472/uncommon-act-of-design-fake-bus-stop-helps-alzheimers-patients

http://www.telegraph.co.uk/news/newstopics/howaboutthat/2071319/Fake-bus-stop-keeps-Alzheimers-patients-from-wandering-off.html

http://www.dailymail.co.uk/health/article-1187774/Alzheimers-sufferers-encouraged-wait-fake-bus-stop-sense-purpose.html