China approves first homegrown COVID-19 vaccine to enter clinical trials

By Elise Ma

One day after the U.S. began the first human trial of an mRNA vaccine candidate for COVID-19 on March 16, China said Tuesday evening that it had approved the first clinical trial of a vaccine candidate developed by domestic researchers.

The vaccine candidate, known as Ad5-nCoV, is a recombinant novel coronavirus vaccine. It was jointly developed by Tianjin-based Cansino Biologics Inc. and the Institute of Biotechnology of the Academy of Military Medical Sciences. The clinical trial will enroll 108 subjects and take place at Tongji Hospital in Wuhan, the epicenter of COVID-19.

Cansino said Ad5-nCoV is a genetically engineered vaccine candidate with the replication-defective adenovirus type 5 as the vector to express SARS-CoV-2 spike protein. The vaccine candidate is intended to be used to prevent the disease caused by the novel coronavirus infection.

Backed by the state, the company has also obtained support from the Tianjin Science and Technology Bureau through the Project on Emergency Prevention and Control of COVID-19 Infection to develop the vaccine.

On March 17, the company said it has started to prepare for clinical trials of Ad5-nCoV and the pre-screening of healthy volunteers.

Cansino CEO Xuefeng Yu said the company and the academy have been collaborating closely since late January to develop Ad5-nCoV and generate sound scientific data to support its IND filing. “Having committed to providing unconditional support to fight against the global epidemic, Cansino is determined to launch our vaccine product candidate as soon as possible, with no compromises in quality and safety,” he added.

According to the Chinese Clinical Trial Registry, it is a single-center, open and dose-escalation phase I trial testing safety and tolerance of Ad5-nCoV in healthy adults, ages 18 to 60. The low-, middle- and high-dosage groups will each see 36 patients, who will receive 5e10vp, 1E11vp and 1E11vp of Ad5-nCoV, respectively.

The primary indicator is to see whether there are adverse reactions seven days after injection, and the secondary indicators are whether adverse reactions are observed 28 days after injection or severe adverse reactions six months after the injection.

Researchers will also look for anti-S antibody immunoglobulin G, neutralizing antibodies against SARS-CoV-2, neutralizing antibodies against Ad5 and specific T-cell responses as secondary indicators.

Ad5-nCoV is developed with Cansino’s adenovirus-based viral vector vaccine technology platform, which utilizes adenoviruses as viral vectors to deliver vaccine antigens to the human cell. Previously, the technology platform was key in enabling Cansino to translate its Ebola virus disease vaccine, Ad5-EBOV, from a concept to an approved product in merely three years.

A forerunner in China’s vaccine space, Cansino came to the industry’s attention when its Ad5-EBOV became the first approved Ebola virus vaccine in China for emergency use and as part of the national stockpile in October 2017.

Leveraging the existing technology platform, Cansino said results from preclinical animal studies of Ad5-nCoV show that the vaccine candidate can induce strong immune responses in animal models. The preclinical animal safety studies demonstrated a good safety profile.

“We have completed the necessary preclinical steps for vaccine R&D. To date, the GMP clinical batches have passed quality testing and are ready for the phase I clinical trial,” the company said.

Stepping carefully

A cautious scientist, Yu stressed the importance of safety in vaccine development and warned that there is more to think of than just the speed of development.

“We need speed, but we still need quality. We d

on’t want to introduce a second harm to people. It is critically important to check every step,” Yu said in a webinar organized by Chinese CRO Wuxi Apptec last month.

He said although the existing technology platform can speed up the development of a vaccine, there are issues to address before applying any vaccine to a human. Animal models should be available before moving any vaccine candidates into human trials so as to produce a vaccine that will eventually work without concerns such as disease enhancement.

“Even though we have learned from MERS and SARS, COVID-19 is still a new virus that behaves very differently, so we should really get some basic understanding,” Yu said.

And in developing a vaccine for emergency response, Yu said it would be ideal to require just one dose, and developers need to consider the manufacturability of the vaccine in order to benefit more people.

On March 16, the NIH said a phase I trial has begun in Seattle. The vaccine candidate, known as mRNA-1273 and co-developed by NIH and Moderna Inc., encodes viral spike (S) protein for prevention of COVID-19.

https://www.bioworld.com/articles/433791-china-approves-first-homegrown-covid-19-vaccine-to-enter-clinical-trials?id=433791-china-approves-first-homegrown-covid-19-vaccine-to-enter-clinical-trials

Pig-Monkey Hybrid Engineered in China


This piglet had some cells from a monkey but died within a week of birth
Tang Hai

By Michael Le Page

Pig-primate chimeras have been born live for the first time but died within a week. The two piglets, created by a team in China, looked normal although a small proportion of their cells were derived from cynomolgus monkeys.

“This is the first report of full-term pig-monkey chimeras,” says Tang Hai at the State Key Laboratory of Stem Cell and Reproductive Biology in Beijing.

The ultimate aim of the work is to grow human organs in animals for transplantation. But the results show there is still a long way to go to achieve this, the team says.

Hai and his colleagues genetically modified cynomolgus monkey cells growing in culture so they produced a fluorescent protein called GFP. This enabled the researchers to track the cells and their descendents. They then derived embryonic stem cells from the modified cells and injected them into pig embryos five days after fertilisation.

More than 4000 embryos were implanted in sows. Ten piglets were born as a result, of which two were chimeras. All died within a week. In the chimeric piglets, multiple tissues – including in the heart, liver, spleen, lung and skin – partly consisted of monkey cells, but the proportion was low: between one in 1000 and one in 10,000.

It is unclear why the piglets died, says Hai, but because the non-chimeric pigs died as well, the team suspects it is to do with the IVF process rather than the chimerism. IVF doesn’t work nearly as well in pigs as it does in humans and some other animals.

The team is now trying to create healthy animals with a higher proportion of monkey cells, says Hai. If that is successful, the next step would be to try to create pigs in which one organ is composed almost entirely of primate cells.

Something like this has already been achieved in rodents. In 2010, Hiromitsu Nakauchi, now at Stanford University in California, created mice with rat pancreases by genetically modifying the mice so their own cells couldn’t develop into a pancreas.

Pig-human chimeras

In 2017, Juan Carlos Izpisua Belmonte’s team at the Salk Institute in California created pig-human chimeras, but only around one in 100,000 cells were human and, for ethical reasons, the embryos were only allowed to develop for a month. The concern is that a chimera’s brain could be partly human.

This is why Hai and his team used monkey rather than human cells. But while the proportion of monkey cells in their chimeras is higher than the proportion of human cells in Belmonte’s chimeras, it is still very low.

“Given the extremely low chimeric efficiency and the deaths of all the animals, I actually see this as fairly discouraging,” says stem cell biologist Paul Knoepfler at the University of California, Davis.

He isn’t convinced that it will ever be possible to grow organs suitable for transplantation by creating animal-human chimeras. However, it makes sense to continue researching this approach along with others such as tissue engineering, he says.

According to a July report in the Spanish newspaper El País, Belmonte’s team has now created human-monkey chimeras, in work carried out in China. The results have not yet been published.

While interspecies chimerism doesn’t occur naturally, the bodies of animals including people can consist of a mix of cells. Mothers have cells from their children growing in many of their organs, for instance, a phenomenon called microchimerism.

Journal reference: Protein & Cell, DOI: 10.1007/s13238-019-00676-8

Read more: https://www.newscientist.com/article/2226490-exclusive-two-pigs-engineered-to-have-monkey-cells-born-in-china/#ixzz67RYaU5XS

China’s Lunar Rover Has Found Something Weird on the Far Side of the Moon


Tracks made by Yutu-2 while navigating hazards during lunar day 8, which occurred during late July and early August 2019.

By Andrew Jones

China’s Chang’e-4 lunar rover has discovered an unusually colored, ‘gel-like’ substance during its exploration activities on the far side of the moon.

The mission’s rover, Yutu-2, stumbled on that surprise during lunar day 8. The discovery prompted scientists on the mission to postpone other driving plans for the rover, and instead focus its instruments on trying to figure out what the strange material is.

Day 8 started on July 25; Yutu-2 began navigating a path through an area littered with various small impact craters, with the help and planning of drivers at the Beijing Aerospace Control Center, according to a Yutu-2 ‘drive diary’ published on Aug. 17 by the government-sanctioned Chinese-language publication Our Space, which focuses on space and science communication.

On July 28, the Chang’e-4 team was preparing to power Yutu-2 down for its usual midday ‘nap’ to protect the rover from high temperatures and radiation from the sun high in the sky. A team member checking images from the rover’s main camera spotted a small crater that seemed to contain material with a color and luster unlike that of the surrounding lunar surface.

The drive team, excited by the discovery, called in their lunar scientists. Together, the teams decided to postpone Yutu-2’s plans to continue west and instead ordered the rover to check out the strange material.


Yutu-2 found a strangely-colored substance in a crater on the far side of the moon.

With the help of obstacle-avoidance cameras, Yutu-2 carefully approached the crater and then targeted the unusually colored material and its surroundings. The rover examined both areas with its Visible and Near-Infrared Spectrometer (VNIS), which detects light that is scattered or reflected off materials to reveal their makeup.

VNIS is the same instrument that detected tantalizing evidence of material originating from the lunar mantle in the regolith of Von Kármán crater, a discovery Chinese scientists announced in May.

So far, mission scientists haven’t offered any indication as to the nature of the colored substance and have said only that it is “gel-like” and has an “unusual color.” One possible explanation, outside researchers suggested, is that the substance is melt glass created from meteorites striking the surface of the moon.

Yutu-2’s discovery isn’t scientists’ first lunar surprise, however. Apollo 17 astronaut and geologist Harrison Schmitt discovered orange-colored soil near the mission’s Taurus-Littrow landing site in 1972, prompting excitement from both Schmitt and his moonwalk colleague, Gene Cernan. Lunar geologists eventually concluded that the orange soil was created during an explosive volcanic eruption 3.64 billion years ago.


Strange orange soil was discovered on the moon by the Apollo 17 mission in 1972.

Chang’e-4 launched in early December 2018, and made the first-ever soft landing on the far side of the moon on Jan. 3. The Yutu-2 rover had covered a total of 890 feet (271 meters) by the end of lunar day 8.

The Chang’e-4 lander and Yutu-2 rover powered down for the end of lunar day 8 on Aug. 7, and began their ninth lunar day over the weekend. The Yutu-2 rover woke up at 8:42 p.m. EDT on Aug. 23 (00:42 GMT Aug. 24), and the lander followed the next day, at 8:10 p.m. (00:10 GMT).

https://www.space.com/china-far-side-moon-rover-strange-substance.html

Thanks to Kebmodee for bringing this to the It’s Interesting community.

During lunar day 9, Yutu-2 will continue its journey west, take a precautionary six-day nap around local noontime, and power down for a ninth lunar night around Sept. 5, about 24 hours hours ahead of local sunset.

“Elixir of immortality” found in central China’s ancient tomb

Archaeologists in central China’s Henan Province said Friday that the liquid found in a bronze pot unearthed from a Western Han Dynasty (202 BC-8 AD) tomb is an “elixir of life” recorded in ancient Taoist literature.

About 3.5 liters of the liquid was excavated from the tomb of a noble family in the city of Luoyang last October. It was initially judged by archaeologists to be liquor as it gave off an alcohol aroma.

However, further lab research found that the liquid is mainly made up of potassium nitrate and alunite, the main ingredients of an immortality medicine mentioned in an ancient Taoist text, according to Pan Fusheng, leading archaeologist of the excavation project.

“It is the first time that mythical ‘immortality medicines’ have been found in China,” said Shi Jiazhen, head of the Institute of Cultural Relics and Archaeology in Luoyang.

“The liquid is of significant value for the study of ancient Chinese thoughts on achieving immortality and the evolution of Chinese civilization,” Shi added.

A large number of color-painted clay pots, jadeware and bronze artifacts were also unearthed from the tomb, which covers 210 square meters. The remains of the tomb occupant have also been preserved.

“The tomb provides valuable material for study of the life of Western Han nobles as well as the funeral rituals and customs of the period,” Pan said.

China created what it claims is the first AI news anchor

by Isobel Asher Hamilton

– China’s state press agency has developed what it calls “AI news anchors,” avatars of real-life news presenters that read out news as it is typed.

– It developed the anchors with the Chinese search-engine giant Sogou.

– No details were given as to how the anchors were made, and one expert said they fell into the “uncanny valley,” in which avatars have an unsettling resemblance to humans.

China’s state-run press agency, Xinhua, has unveiled what it claims are the world’s first news anchors generated by artificial intelligence.

Xinhua revealed two virtual anchors at the World Internet Conference on Thursday. Both were modeled on real presenters, with one who speaks Chinese and another who speaks English.

“AI anchors have officially become members of the Xinhua News Agency reporting team,” Xinhua told the South China Morning Post. “They will work with other anchors to bring you authoritative, timely, and accurate news information in both Chinese and English.”

In a post, Xinhua said the generated anchors could work “24 hours a day” on its website and various social-media platforms, “reducing news production costs and improving efficiency.”

Xinhua developed the virtual anchors with Sogou, China’s second-biggest search engine. No details were given about how they were made.

Though Xinhua presents the avatars as independently learning from “live broadcasting videos,” the avatars do not appear to rely on true artificial intelligence, as they simply read text written by humans.

“I will work tirelessly to keep you informed as texts will be typed into my system uninterrupted,” the English-speaking anchor says in its first video, using a synthesized voice.

The Oxford computer-science professor Michael Wooldridge told the BBC that the anchor fell into the “uncanny valley,” in which avatars or objects that closely but do not fully resemble humans make observers more uncomfortable than ones that are more obviously artificial.

https://www.businessinsider.com/ai-news-anchor-created-by-china-xinhua-news-agency-2018-11

The Chinese government plans to launch its Social Credit System in 2020 to judge the trustworthiness – or otherwise – of its 1.3 billion residents

In June 14, 2014, the State Council of China published an ominous-sounding document called “Planning Outline for the Construction of a Social Credit System”. In the way of Chinese policy documents, it was a lengthy and rather dry affair, but it contained a radical idea. What if there was a national trust score that rated the kind of citizen you were?

Imagine a world where many of your daily activities were constantly monitored and evaluated: what you buy at the shops and online; where you are at any given time; who your friends are and how you interact with them; how many hours you spend watching content or playing video games; and what bills and taxes you pay (or not). It’s not hard to picture, because most of that already happens, thanks to all those data-collecting behemoths like Google, Facebook and Instagram or health-tracking apps such as Fitbit. But now imagine a system where all these behaviours are rated as either positive or negative and distilled into a single number, according to rules set by the government. That would create your Citizen Score and it would tell everyone whether or not you were trustworthy. Plus, your rating would be publicly ranked against that of the entire population and used to determine your eligibility for a mortgage or a job, where your children can go to school – or even just your chances of getting a date.

A futuristic vision of Big Brother out of control? No, it’s already getting underway in China, where the government is developing the Social Credit System (SCS) to rate the trustworthiness of its 1.3 billion citizens. The Chinese government is pitching the system as a desirable way to measure and enhance “trust” nationwide and to build a culture of “sincerity”. As the policy states, “It will forge a public opinion environment where keeping trust is glorious. It will strengthen sincerity in government affairs, commercial sincerity, social sincerity and the construction of judicial credibility.”

Others are less sanguine about its wider purpose. “It is very ambitious in both depth and scope, including scrutinising individual behaviour and what books people are reading. It’s Amazon’s consumer tracking with an Orwellian political twist,” is how Johan Lagerkvist, a Chinese internet specialist at the Swedish Institute of International Affairs, described the social credit system. Rogier Creemers, a post-doctoral scholar specialising in Chinese law and governance at the Van Vollenhoven Institute at Leiden University, who published a comprehensive translation of the plan, compared it to “Yelp reviews with the nanny state watching over your shoulder”.

For now, technically, participating in China’s Citizen Scores is voluntary. But by 2020 it will be mandatory. The behaviour of every single citizen and legal person (which includes every company or other entity)in China will be rated and ranked, whether they like it or not.

Prior to its national roll-out in 2020, the Chinese government is taking a watch-and-learn approach. In this marriage between communist oversight and capitalist can-do, the government has given a licence to eight private companies to come up with systems and algorithms for social credit scores. Predictably, data giants currently run two of the best-known projects.

The first is with China Rapid Finance, a partner of the social-network behemoth Tencent and developer of the messaging app WeChat with more than 850 million active users. The other, Sesame Credit, is run by the Ant Financial Services Group (AFSG), an affiliate company of Alibaba. Ant Financial sells insurance products and provides loans to small- to medium-sized businesses. However, the real star of Ant is AliPay, its payments arm that people use not only to buy things online, but also for restaurants, taxis, school fees, cinema tickets and even to transfer money to each other.

Sesame Credit has also teamed up with other data-generating platforms, such as Didi Chuxing, the ride-hailing company that was Uber’s main competitor in China before it acquired the American company’s Chinese operations in 2016, and Baihe, the country’s largest online matchmaking service. It’s not hard to see how that all adds up to gargantuan amounts of big data that Sesame Credit can tap into to assess how people behave and rate them accordingly.

So just how are people rated? Individuals on Sesame Credit are measured by a score ranging between 350 and 950 points. Alibaba does not divulge the “complex algorithm” it uses to calculate the number but they do reveal the five factors taken into account. The first is credit history. For example, does the citizen pay their electricity or phone bill on time? Next is fulfilment capacity, which it defines in its guidelines as “a user’s ability to fulfil his/her contract obligations”. The third factor is personal characteristics, verifying personal information such as someone’s mobile phone number and address. But the fourth category, behaviour and preference, is where it gets interesting.

Under this system, something as innocuous as a person’s shopping habits become a measure of character. Alibaba admits it judges people by the types of products they buy. “Someone who plays video games for ten hours a day, for example, would be considered an idle person,” says Li Yingyun, Sesame’s Technology Director. “Someone who frequently buys diapers would be considered as probably a parent, who on balance is more likely to have a sense of responsibility.” So the system not only investigates behaviour – it shapes it. It “nudges” citizens away from purchases and behaviours the government does not like.

Friends matter, too. The fifth category is interpersonal relationships. What does their choice of online friends and their interactions say about the person being assessed? Sharing what Sesame Credit refers to as “positive energy” online, nice messages about the government or how well the country’s economy is doing, will make your score go up.

Alibaba is adamant that, currently, anything negative posted on social media does not affect scores (we don’t know if this is true or not because the algorithm is secret). But you can see how this might play out when the government’s own citizen score system officially launches in 2020. Even though there is no suggestion yet that any of the eight private companies involved in the ongoing pilot scheme will be ultimately responsible for running the government’s own system, it’s hard to believe that the government will not want to extract the maximum amount of data for its SCS, from the pilots. If that happens, and continues as the new normal under the government’s own SCS it will result in private platforms acting essentially as spy agencies for the government. They may have no choice.

Posting dissenting political opinions or links mentioning Tiananmen Square has never been wise in China, but now it could directly hurt a citizen’s rating. But here’s the real kicker: a person’s own score will also be affected by what their online friends say and do, beyond their own contact with them. If someone they are connected to online posts a negative comment, their own score will also be dragged down.

So why have millions of people already signed up to what amounts to a trial run for a publicly endorsed government surveillance system? There may be darker, unstated reasons – fear of reprisals, for instance, for those who don’t put their hand up – but there is also a lure, in the form of rewards and “special privileges” for those citizens who prove themselves to be “trustworthy” on Sesame Credit.

If their score reaches 600, they can take out a Just Spend loan of up to 5,000 yuan (around £565) to use to shop online, as long as it’s on an Alibaba site. Reach 650 points, they may rent a car without leaving a deposit. They are also entitled to faster check-in at hotels and use of the VIP check-in at Beijing Capital International Airport. Those with more than 666 points can get a cash loan of up to 50,000 yuan (£5,700), obviously from Ant Financial Services. Get above 700 and they can apply for Singapore travel without supporting documents such as an employee letter. And at 750, they get fast-tracked application to a coveted pan-European Schengen visa. “I think the best way to understand the system is as a sort of bastard love child of a loyalty scheme,” says Creemers.

Higher scores have already become a status symbol, with almost 100,000 people bragging about their scores on Weibo (the Chinese equivalent of Twitter) within months of launch. A citizen’s score can even affect their odds of getting a date, or a marriage partner, because the higher their Sesame rating, the more prominent their dating profile is on Baihe.

Sesame Credit already offers tips to help individuals improve their ranking, including warning about the downsides of friending someone who has a low score. This might lead to the rise of score advisers, who will share tips on how to gain points, or reputation consultants willing to offer expert advice on how to strategically improve a ranking or get off the trust-breaking blacklist.

Indeed, Sesame Credit is basically a big data gamified version of the Communist Party’s surveillance methods; the disquieting dang’an. The regime kept a dossier on every individual that tracked political and personal transgressions. A citizen’s dang’an followed them for life, from schools to jobs. People started reporting on friends and even family members, raising suspicion and lowering social trust in China. The same thing will happen with digital dossiers. People will have an incentive to say to their friends and family, “Don’t post that. I don’t want you to hurt your score but I also don’t want you to hurt mine.”

We’re also bound to see the birth of reputation black markets selling under-the-counter ways to boost trustworthiness. In the same way that Facebook Likes and Twitter followers can be bought, individuals will pay to manipulate their score. What about keeping the system secure? Hackers (some even state-backed) could change or steal the digitally stored information.

The new system reflects a cunning paradigm shift. As we’ve noted, instead of trying to enforce stability or conformity with a big stick and a good dose of top-down fear, the government is attempting to make obedience feel like gaming. It is a method of social control dressed up in some points-reward system. It’s gamified obedience.

In a trendy neighbourhood in downtown Beijing, the BBC news services hit the streets in October 2015 to ask people about their Sesame Credit ratings. Most spoke about the upsides. But then, who would publicly criticise the system? Ding, your score might go down. Alarmingly, few people understood that a bad score could hurt them in the future. Even more concerning was how many people had no idea that they were being rated.

Currently, Sesame Credit does not directly penalise people for being “untrustworthy” – it’s more effective to lock people in with treats for good behaviour. But Hu Tao, Sesame Credit’s chief manager, warns people that the system is designed so that “untrustworthy people can’t rent a car, can’t borrow money or even can’t find a job”. She has even disclosed that Sesame Credit has approached China’s Education Bureau about sharing a list of its students who cheated on national examinations, in order to make them pay into the future for their dishonesty.

Penalties are set to change dramatically when the government system becomes mandatory in 2020. Indeed, on September 25, 2016, the State Council General Office updated its policy entitled “Warning and Punishment Mechanisms for Persons Subject to Enforcement for Trust-Breaking”. The overriding principle is simple: “If trust is broken in one place, restrictions are imposed everywhere,” the policy document states.

For instance, people with low ratings will have slower internet speeds; restricted access to restaurants, nightclubs or golf courses; and the removal of the right to travel freely abroad with, I quote, “restrictive control on consumption within holiday areas or travel businesses”. Scores will influence a person’s rental applications, their ability to get insurance or a loan and even social-security benefits. Citizens with low scores will not be hired by certain employers and will be forbidden from obtaining some jobs, including in the civil service, journalism and legal fields, where of course you must be deemed trustworthy. Low-rating citizens will also be restricted when it comes to enrolling themselves or their children in high-paying private schools. I am not fabricating this list of punishments. It’s the reality Chinese citizens will face. As the government document states, the social credit system will “allow the trustworthy to roam everywhere under heaven while making it hard for the discredited to take a single step”.

According to Luciano Floridi, a professor of philosophy and ethics of information at the University of Oxford and the director of research at the Oxford Internet Institute, there have been three critical “de-centering shifts” that have altered our view in self-understanding: Copernicus’s model of the Earth orbiting the Sun; Darwin’s theory of natural selection; and Freud’s claim that our daily actions are controlled by the unconscious mind.

Floridi believes we are now entering the fourth shift, as what we do online and offline merge into an onlife. He asserts that, as our society increasingly becomes an infosphere, a mixture of physical and virtual experiences, we are acquiring an onlife personality – different from who we innately are in the “real world” alone. We see this writ large on Facebook, where people present an edited or idealised portrait of their lives. Think about your Uber experiences. Are you just a little bit nicer to the driver because you know you will be rated? But Uber ratings are nothing compared to Peeple, an app launched in March 2016, which is like a Yelp for humans. It allows you to assign ratings and reviews to everyone you know – your spouse, neighbour, boss and even your ex. A profile displays a “Peeple Number”, a score based on all the feedback and recommendations you receive. Worryingly, once your name is in the Peeple system, it’s there for good. You can’t opt out.

Peeple has forbidden certain bad behaviours including mentioning private health conditions, making profanities or being sexist (however you objectively assess that). But there are few rules on how people are graded or standards about transparency.

China’s trust system might be voluntary as yet, but it’s already having consequences. In February 2017, the country’s Supreme People’s Court announced that 6.15 million of its citizens had been banned from taking flights over the past four years for social misdeeds. The ban is being pointed to as a step toward blacklisting in the SCS. “We have signed a memorandum… [with over] 44 government departments in order to limit ‘discredited’ people on multiple levels,” says Meng Xiang, head of the executive department of the Supreme Court. Another 1.65 million blacklisted people cannot take trains.

Where these systems really descend into nightmarish territory is that the trust algorithms used are unfairly reductive. They don’t take into account context. For instance, one person might miss paying a bill or a fine because they were in hospital; another may simply be a freeloader. And therein lies the challenge facing all of us in the digital world, and not just the Chinese. If life-determining algorithms are here to stay, we need to figure out how they can embrace the nuances, inconsistencies and contradictions inherent in human beings and how they can reflect real life.

You could see China’s so-called trust plan as Orwell’s 1984 meets Pavlov’s dogs. Act like a good citizen, be rewarded and be made to think you’re having fun. It’s worth remembering, however, that personal scoring systems have been present in the west for decades.

More than 70 years ago, two men called Bill Fair and Earl Isaac invented credit scores. Today, companies use FICO scores to determine many financial decisions, including the interest rate on our mortgage or whether we should be given a loan.

For the majority of Chinese people, they have never had credit scores and so they can’t get credit. “Many people don’t own houses, cars or credit cards in China, so that kind of information isn’t available to measure,” explains Wen Quan, an influential blogger who writes about technology and finance. “The central bank has the financial data from 800 million people, but only 320 million have a traditional credit history.” According to the Chinese Ministry of Commerce, the annual economic loss caused by lack of credit information is more than 600 billion yuan (£68bn).

China’s lack of a national credit system is why the government is adamant that Citizen Scores are long overdue and badly needed to fix what they refer to as a “trust deficit”. In a poorly regulated market, the sale of counterfeit and substandard products is a massive problem. According to the Organization for Economic Co-operation and Development (OECD), 63 per cent of all fake goods, from watches to handbags to baby food, originate from China. “The level of micro corruption is enormous,” Creemers says. “So if this particular scheme results in more effective oversight and accountability, it will likely be warmly welcomed.”

The government also argues that the system is a way to bring in those people left out of traditional credit systems, such as students and low-income households. Professor Wang Shuqin from the Office of Philosophy and Social Science at Capital Normal University in China recently won the bid to help the government develop the system that she refers to as “China’s Social Faithful System”. Without such a mechanism, doing business in China is risky, she stresses, as about half of the signed contracts are not kept. “Given the speed of the digital economy it’s crucial that people can quickly verify each other’s credit worthiness,” she says. “The behaviour of the majority is determined by their world of thoughts. A person who believes in socialist core values is behaving more decently.” She regards the “moral standards” the system assesses, as well as financial data, as a bonus.

Indeed, the State Council’s aim is to raise the “honest mentality and credit levels of the entire society” in order to improve “the overall competitiveness of the country”. Is it possible that the SCS is in fact a more desirably transparent approach to surveillance in a country that has a long history of watching its citizens? “As a Chinese person, knowing that everything I do online is being tracked, would I rather be aware of the details of what is being monitored and use this information to teach myself how to abide by the rules?” says Rasul Majid, a Chinese blogger based in Shanghai who writes about behavioural design and gaming psychology. “Or would I rather live in ignorance and hope/wish/dream that personal privacy still exists and that our ruling bodies respect us enough not to take advantage?” Put simply, Majid thinks the system gives him a tiny bit more control over his data.

When I tell westerners about the Social Credit System in China, their responses are fervent and visceral. Yet we already rate restaurants, movies, books and even doctors. Facebook, meanwhile, is now capable of identifying you in pictures without seeing your face; it only needs your clothes, hair and body type to tag you in an image with 83 per cent accuracy.

In 2015, the OECD published a study revealing that in the US there are at least 24.9 connected devices per 100 inhabitants. All kinds of companies scrutinise the “big data” emitted from these devices to understand our lives and desires, and to predict our actions in ways that we couldn’t even predict ourselves.

Governments around the world are already in the business of monitoring and rating. In the US, the National Security Agency (NSA) is not the only official digital eye following the movements of its citizens. In 2015, the US Transportation Security Administration proposed the idea of expanding the PreCheck background checks to include social-media records, location data and purchase history. The idea was scrapped after heavy criticism, but that doesn’t mean it’s dead. We already live in a world of predictive algorithms that determine if we are a threat, a risk, a good citizen and even if we are trustworthy. We’re getting closer to the Chinese system – the expansion of credit scoring into life scoring – even if we don’t know we are.

So are we heading for a future where we will all be branded online and data-mined? It’s certainly trending that way. Barring some kind of mass citizen revolt to wrench back privacy, we are entering an age where an individual’s actions will be judged by standards they can’t control and where that judgement can’t be erased. The consequences are not only troubling; they’re permanent. Forget the right to delete or to be forgotten, to be young and foolish.

While it might be too late to stop this new era, we do have choices and rights we can exert now. For one thing, we need to be able rate the raters. In his book The Inevitable, Kevin Kelly describes a future where the watchers and the watched will transparently track each other. “Our central choice now is whether this surveillance is a secret, one-way panopticon – or a mutual, transparent kind of ‘coveillance’ that involves watching the watchers,” he writes.

Our trust should start with individuals within government (or whoever is controlling the system). We need trustworthy mechanisms to make sure ratings and data are used responsibly and with our permission. To trust the system, we need to reduce the unknowns. That means taking steps to reduce the opacity of the algorithms. The argument against mandatory disclosures is that if you know what happens under the hood, the system could become rigged or hacked. But if humans are being reduced to a rating that could significantly impact their lives, there must be transparency in how the scoring works.

In China, certain citizens, such as government officials, will likely be deemed above the system. What will be the public reaction when their unfavourable actions don’t affect their score? We could see a Panama Papers 3.0 for reputation fraud.

It is still too early to know how a culture of constant monitoring plus rating will turn out. What will happen when these systems, charting the social, moral and financial history of an entire population, come into full force? How much further will privacy and freedom of speech (long under siege in China) be eroded? Who will decide which way the system goes? These are questions we all need to consider, and soon. Today China, tomorrow a place near you. The real questions about the future of trust are not technological or economic; they are ethical.

If we are not vigilant, distributed trust could become networked shame. Life will become an endless popularity contest, with us all vying for the highest rating that only a few can attain.

https://www.wired.co.uk/article/chinese-government-social-credit-score-privacy-invasion

Chinese firm halves worker costs by hiring army of robots to sort out 200,000 packages a day

A viral video showing an army of little orange robots sorting out packages in a warehouse in eastern China is the latest example of how machines are increasingly taking over menial factory work on the mainland.

The behind-the-scenes footage of the self-charging robot army in a sorting centre of Chinese delivery powerhouse Shentong (STO) Express was shared on People’s Daily’s social media accounts on Sunday.

The video showed dozens of round orange Hikvision robots – each the size of a seat cushion – swivelling across the floor of the large warehouse in Hangzhou, Zhejiang province.

A worker was seen feeding each robot with a package before the machines carried the parcels away to different areas around the sorting centre, then flipping their lids to deposit them into chutes beneath the floor.

The robots identified the destination of each package by scanning a code on the parcel, thus minimising sorting mistakes, according to the video.

The machines can sort up to 200,000 packages a day and are self-charging, meaning they can operate around the clock.

An STO Express spokesman told the South China Morning Post on Monday that the robots had helped the company save half the costs it typically required to use human workers.

They also improved efficiency by around 30 per cent and maximised sorting accuracy, he said.

“We use these robots in two of our centres in Hangzhou right now,” the spokesman said. “We want to start using these across the country, especially in our bigger centres.”

Although the machines could run around the clock, they were presently used only for about six or seven hours each time from 6pm, he said.

Manufacturers across China have been increasingly replacing human workers with machines.

The output of industrial robots in the country grew 30.4 per cent last year.

In the country’s latest five-year plan, the central government set a target aiming for annual production of these robots to reach 100,000 by 2020.

Apple’s supplier Foxconn last year replaced 60,000 factory workers with robots, according to a Chinese government official in Kunshan, eastern Jiangsu province.

The Taiwanese smartphone maker has several factories across China.

http://www.scmp.com/news/china/society/article/2086662/chinese-firm-cuts-costs-hiring-army-robots-sort-out-200000

Thanks to Kebmodee for bringing this to the It’s Interesting community.

Boy cuts off his index finger during argument with father over phone use

The 11-year-old boy, from Suzhou, China, is said to have sliced off the digit after having an argument with his father about his smartphone addiction.

As his father chastised him for being constantly glued to his phone, the boy is said to have grabbed a knife and plunged it into his left index finger in a fit of rage.

The argument is said to have started when his father told him to put down the phone and help his brother with his homework.

The boy was taken to hospital where surgeon Ren Zhourong attempted to reattach the severed finger during a three-hour operation.

It will be a week until doctors know if the surgery was a success.

Boy ‘cuts off finger during argument with father over phone use’

China Telescope to Displace 9,000 Villagers in Hunt for Extraterrestrials

By EDWARD WONG

The Chinese government is relocating thousands of villagers to complete construction by September of the world’s biggest radio telescope, whose intended purpose is to detect signs of extraterrestrial life.

The telescope would be 500 meters, or 1,640 feet, in diameter, by far the largest of its kind in the world. It is called FAST, for Five-hundred-meter Aperture Spherical Telescope, and costs an estimated 1.2 billion renminbi, or $184 million.

The mass relocation was announced on Tuesday in a report by Xinhua, the state news agency. The report said officials were relocating 2,029 families, a total of 9,110 people, living within a three-mile radius of the telescope in the area of Pingtang and Luodian Counties in the southwestern province of Guizhou.

Officials plan to give each person the equivalent of $1,800 for housing compensation, the report said. Guizhou is one of China’s poorest provinces.

Forced relocations for infrastructure projects are common across China, and the people being moved by officials often complain both of the eviction from their homes and inadequate compensation. The Three Gorges Dam displaced more than one million people along the Yangtze River, and the middle route of the gargantuan South-North Water Diversion Project has resulted in the relocation of 350,000 people to make way for a series of canals.

The Chinese government has announced ambitious plans for its space program, at a time when the American one is in retreat. China aims to put an astronaut on the moon and a space station in orbit. The FAST project is another important element in the larger plan.

The telescope is being built in a wide depression among karst hills. The depression is far from cities and ideal for picking up radio transmissions, the Xinhua report said. Scientists began looking for a site in 1994 and finally settled on the Dawodang depression.

If the truth is out there, then some Chinese scientists are confident that the giant telescope will find it. The current largest operational radio telescope is the 300-meter-diameter Arecibo Observatory in Puerto Rico, but FAST in Guizhou will far surpass that.

Li Di, a chief scientist with the National Astronomical Observatories under the Chinese Academy of Sciences, told China Daily last year that “with a larger signal receiving area and more flexibility, FAST will be able to scan two times more sky area than Arecibo, with three to five times higher sensitivity.”

Last November, scientists successfully tested the telescope’s “retina,” which weighs 33 tons and is suspended 460 to 525 feet above the reflector dish, which was half-finished at the time, China Daily reported.

The telescope has 4,500 panels that are mostly triangular and whose sides measure 36 feet, the report said. Those create a parabolic shape. The panels move and, by doing so, alter the shape of the antenna, which is supposed to pick up radio signals from distant corners of the universe. Those signals would then be reflected to a focal point.

Mr. Li told China Daily that engineers were aiming to install all the panels by this June and complete debugging by September.

“Ultimately, exploring the unknown is the nature of mankind,” he said, adding that it was “as visceral as feeding and clothing ourselves.”

“It drives us to a greater future,” he said.